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JCF Excitatory DREADD Functional Validation (view source)
Revision as of 15:36, 27 February 2024
, 27 February→Agenda
| Name = Clozapine-N-Oxide Taste Aversion
| Name = Clozapine-N-Oxide Taste Aversion
| project = DREADDs and Magentic Field
| project = DREADDs and Magentic Field
| code = JCE
| code = JCF
| protocol = 202200000006
| protocol = 202200000006
| funding = Chair's Fund
| funding = Chair's Fund
| investigators = Cote, Houpt
| investigators = Cote, Houpt
| species = mice
| species = mice
| date = 2023-6-19
| date = 2024-1-28
| type = CTA
| type = CTA
| drugs = NaCl, CNO
| drugs = NaCl, CNO
'''Day 0: Water removed''' (2023-9-12)
'''Day 0: Water removed''' (**2024-7-19)
In the afternoon (~4pm), mice will be given supplemental access to water for 30 min.
In the afternoon (~4pm), mice will be given supplemental access to water for 30 min.
'''Day 12: Conditioning Day''' (2023-9-24)
'''Day 12: Conditioning Day''' (2024-2-28)
Mice are given 10-min access to 0.125% saccharin solution, then injected with CNO (3mg/kg,10ml/kg, i.p) after 10 min
Mice are given 10-min access to 0.125% saccharin solution, then injected with CNO (3mg/kg,10ml/kg, i.p) after 15 min
Groups:
Groups: