Difference between revisions of "C-Fos-Cre DREADD"

Latest revision as of 10:16, 2 February 2023

Chemogenetic expression of DREADD receptors in c-Fos-positive cells after stimulation
Schematic timeline of recapitulating stimulation with excitatory DREADDs
Schematic timeline of attenuating stimulation with inhibitory DREADDs

(Z)-4-Hydroxytamoxifen , Sigma-Aldrich H7904-5MG

Clozapine N-oxide (CNO) . APExBIO A3317 10mg

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+== Overview ==
+<gallery mode="traditional" widths=300px heights=300px>
+Fos-Cre-DREADD-schema.png|Chemogenetic expression of DREADD receptors in c-Fos-positive cells after stimulation
+Excitatory-DREADD-schema.png|Schematic timeline of recapitulating stimulation with excitatory DREADDs
+Inhibitory-DREADD-schema.png|Schematic timeline of attenuating stimulation with inhibitory DREADDs
+</gallery>
 == Mouse Strains ==
+=== Fos-CreER ===
+[https://www.jax.org/strain/030323 Fos-tm2.1(icre/ERT2)Luo (JAX 030323)]
+=== hM3Dq ===
+[https://www.jax.org/strain/026220 B6N;129-Tg(CAG-CHRM3*,-mCitrine)1Ute/J, aka CAG-LSL-Gq-DREADD (JAX 026220)]
+=== hM4Di ===
+[https://www.jax.org/strain/026219 B6N.129-Gt(ROSA)26Sortm1(CAG-CHRM4*,-mCitrine)Ute/J, aka R26-LSL-Gi-DREADD (JAX 026219)]
+=== C57BL/6J (Controls) ===
+[https://www.jax.org/strain/000664 C57BL/6J (JAX 000664)]
 == Reagents ==