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DMV Valproate 100mg/kg Controls (view source)
Revision as of 10:41, 30 November 2022
, 10:41, 30 November 2022created page
Fill in some saline controls for Valproate enhancement of saccharin-LiCl CTA.
{{Infobox experiment|align=right
| Name = DMV Valproate Controls
| project = HDAC Sex Difference
| code = DMV
| protocol = 202200000006
| funding = Chair's Fund
| investigators = Mukherjee, Bass, Houpt
| species = rat
| date = 2022-12-1
| type = CTA
| drugs = valproate, lithium
| artifacts =
| data = https://houptlab.org/bartab/expt/?id=DMV
}}
==Data==
'''[https://houptlab.org/bartab/expt/?id=DMS Raw Data Link]'''
==People==
Marena Bass
Durba Mukherjee (in absentia)
==Agenda==
'''Rats arrive (2202-11-22)'''
Sprague Dawley rats (dob males: 2022-???; females: 2022-???? )
'''Day 0: Water removed 2022-12-1'''
<br>
'''Days 1-8: Water Restriction 2022-12-2 thru 2022-12-9'''
Weigh rats daily. Water for 10 min, ad lib food.
10 min water at 1400 daily.
<br>
'''Day 9: Conditioning Day 2022-12-10'''
* -15 min: 8 ml/kg of 0.15M LiCl
* 0-30 min: saccharin 0.125%
* at 30 min: 3 ml/kg ip of 0.15M LiCl or NaCl
Groups:
* DMV01-04 NaCl-Li-Male
* DMV05-08 NaCl-NaCl-Male
* DMV09-12 NaCl-Li-Female
* DMV13-16 NaCl-NaCl-Female
ad lib water returned after final injection overnight.
<br>
'''Days 10-21: Preference Tests: 2022-12-11 to 2022-12-23'''
Rats CTA acquisition and extinction was measured with 24-h, 2-bottle preference tests (for 12 days). Rats were given 24-h free access to both 0.125% saccharin and water bottles, alternating position for 10 days.
[[Category:Taste Aversion]]
[[Category:CTA Experiments]]
[[Category:Epigenetics]]
{{Infobox experiment|align=right
| Name = DMV Valproate Controls
| project = HDAC Sex Difference
| code = DMV
| protocol = 202200000006
| funding = Chair's Fund
| investigators = Mukherjee, Bass, Houpt
| species = rat
| date = 2022-12-1
| type = CTA
| drugs = valproate, lithium
| artifacts =
| data = https://houptlab.org/bartab/expt/?id=DMV
}}
==Data==
'''[https://houptlab.org/bartab/expt/?id=DMS Raw Data Link]'''
==People==
Marena Bass
Durba Mukherjee (in absentia)
==Agenda==
'''Rats arrive (2202-11-22)'''
Sprague Dawley rats (dob males: 2022-???; females: 2022-???? )
'''Day 0: Water removed 2022-12-1'''
<br>
'''Days 1-8: Water Restriction 2022-12-2 thru 2022-12-9'''
Weigh rats daily. Water for 10 min, ad lib food.
10 min water at 1400 daily.
<br>
'''Day 9: Conditioning Day 2022-12-10'''
* -15 min: 8 ml/kg of 0.15M LiCl
* 0-30 min: saccharin 0.125%
* at 30 min: 3 ml/kg ip of 0.15M LiCl or NaCl
Groups:
* DMV01-04 NaCl-Li-Male
* DMV05-08 NaCl-NaCl-Male
* DMV09-12 NaCl-Li-Female
* DMV13-16 NaCl-NaCl-Female
ad lib water returned after final injection overnight.
<br>
'''Days 10-21: Preference Tests: 2022-12-11 to 2022-12-23'''
Rats CTA acquisition and extinction was measured with 24-h, 2-bottle preference tests (for 12 days). Rats were given 24-h free access to both 0.125% saccharin and water bottles, alternating position for 10 days.
[[Category:Taste Aversion]]
[[Category:CTA Experiments]]
[[Category:Epigenetics]]