1,145
edits
Changes
added naringin and azauracil doses
From Pacholko 2023 PMID 37356352: LiOr was synthesized by combining lithium hydroxide (Sigma-Aldrich), and orotic acid (Sigma-Aldrich) in a 1:1 M ratio in distilled water; the NaCl concentration was
From Pacholko 2023 PMID 37356352: LiOr was synthesized by combining lithium hydroxide (Sigma-Aldrich), and orotic acid (Sigma-Aldrich) in a 1:1 M ratio in distilled water; the NaCl concentration was
adjusted to 0.9% and pH to 7.4.
adjusted to 0.9% and pH to 7.4.
Also from Pacholko 2023: in mice, 100 mg/kg naringin (inhibitor of Organic anion transporting polypeptides
(OATPs) OATP1A2/Oatp1a1/Oatp1a4) and/or 30 mg/kg 6-azauracil (inhibitor of uridine monophosphate synthase (UMPS), which decarboxylases orotic acid) delivered via IP injection (both dissolved in isotonic saline).
== Milliequivalents ==
== Milliequivalents ==