Ketofen
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This is page on Ketofen
Ingredient | MW | g | volume | g/l | Molarity | Osmolarity |
Ketofen | 254.3 | 0.625 | 0.05 | 12.5 | 0.049154542 | 0.098309084 |
NaHC03 | 84 | 0.25 | 0.05 | 5 | 0.05952381 | 0.119047619 |
To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing. (Source: http://www.wipo.int/patentscope/search/en/WO2004054541)
To mix a ketofen solution of 12.5mg/mL for systemic injection: 625mg ketofen 250mg potassium bicarbonate 50mL ddH2O -Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains. Average rat gets 0.2ul subcutaneously (containing 2.5mg ketofen)