Difference between revisions of "Ketofen"
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m (source added) |
(dose per rat) |
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(Source: http://www.wipo.int/pctdb/en/wo.jsp?IA=US2003039544&WO=2004054541&DISPLAY=DESC) | (Source: http://www.wipo.int/pctdb/en/wo.jsp?IA=US2003039544&WO=2004054541&DISPLAY=DESC) | ||
| − | To mix a ketofen solution for systemic injection: | + | To mix a ketofen solution of 12.5mg/mL for systemic injection: |
625mg ketofen | 625mg ketofen | ||
250mg potassium bicarbonate | 250mg potassium bicarbonate | ||
| Line 19: | Line 19: | ||
-Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains. | -Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains. | ||
| + | |||
| + | Average rat gets 0.2ul subcutaneously (containing 2.5mg ketofen) | ||
Revision as of 22:08, 3 March 2009
This is page on Ketofen
| -Ingredient MW g volume g/l Molarity Osmolarity |
| Ketofen 254.3 0.625 0.05 12.5 0.049154542 0.098309084 |
| NaHC03 84 0.25 0.05 5 0.05952381 0.119047619 |
To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing. (Source: http://www.wipo.int/pctdb/en/wo.jsp?IA=US2003039544&WO=2004054541&DISPLAY=DESC)
To mix a ketofen solution of 12.5mg/mL for systemic injection:
625mg ketofen
250mg potassium bicarbonate
50mL ddH2O
-Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains.
Average rat gets 0.2ul subcutaneously (containing 2.5mg ketofen)