Ketofen

This is page on Ketofen

Ingredient	MW	g	volume	g/l	Molarity	Osmolarity
Ketofen	254.3	0.625	0.05	12.5	0.049154542	0.098309084
NaHC03	84	0.25	0.05	5	0.05952381	0.119047619

To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing. (Source: http://www.wipo.int/patentscope/search/en/WO2004054541)

 To mix a ketofen solution of 12.5mg/mL for systemic injection:
     625mg ketofen
     250mg potassium bicarbonate
       50mL ddH2O
                               
                   -Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains.

     Average rat gets 0.2ul subcutaneously (containing 2.5mg ketofen)