Difference between revisions of "Ketofen"

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(ketofen solution instructions)
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Ingredient MW g volume g/l Molarity Osmolarity
 
Ingredient MW g volume g/l Molarity Osmolarity
 
Ketofen 254.3 0.625 0.05 12.5 0.049154542 0.098309084
 
Ketofen 254.3 0.625 0.05 12.5 0.049154542 0.098309084
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To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing.  
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To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing.
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(Source: http://www.wipo.int/patentscope/search/en/WO2004054541)
  
   To mix a ketofen solution for systemic injection:
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   To mix a ketofen solution of 12.5mg/mL for systemic injection:
 
       625mg ketofen
 
       625mg ketofen
 
       250mg potassium bicarbonate
 
       250mg potassium bicarbonate
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                     -Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains.
 
                     -Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains.
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      Average rat gets 0.2ul subcutaneously (containing 2.5mg ketofen)

Latest revision as of 15:21, 4 July 2022

This is page on Ketofen


Ingredient MW g volume g/l Molarity -Osmolarity
Ketofen 254.3 0.625 0.05 12.5 0.049154542 0.098309084
NaHC03 84 0.25 0.05 5 0.05952381 0.119047619


To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing. (Source: http://www.wipo.int/patentscope/search/en/WO2004054541)

 To mix a ketofen solution of 12.5mg/mL for systemic injection:
     625mg ketofen
     250mg potassium bicarbonate
       50mL ddH2O
                               
                   -Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains.

     Average rat gets 0.2ul subcutaneously (containing 2.5mg ketofen)