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C-Fos Posttranslational Modifications (view source)
Revision as of 14:46, 3 December 2008
, 14:46, 3 December 2008added FBR Myristylation
==Nitrosylation==
==Nitrosylation==
==Myristylation==
Oncogenic FBR v-Fos is myristylated, but c-Fos is not.
From Jotte and Holt 1996 PMID 8896601
"FBR v-fos is expressed as a 75-kD nuclear protein that differs from c-Fos by deletion and replacement of both NH2- and COOH-terminal regions with retroviral gag and mouse fox sequences, respectively....FBR v-los (Jotte et al., 1994). The altered transcrip- tional properties of FBR v-fos are dependent upon its myristylated NH2-terminal glycine."