To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing.
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To mix a ketofen solution for systemic injection:
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625mg ketofen
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250mg potassium bicarbonate
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50mL ddH2O
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-Heat H2O; add bicarbonate and mix with stir bar until dissolved. Add ketofen and mix until the foaming subsides and a clear solution remains.