Changes

To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing.

To get ketofen into solution, for every 2.5mg ketofen, add 1mg bicarbonate (preferably potassium but sodium works too). Heat to ~55-65 degrees C during mixing.

(Source: http://www.wipo.int/pctdb/en/wo.jsp?IA=US2003039544&WO=2004054541&DISPLAY=DESC)  

(Source: http://www.wipo.int/patentscope/search/en/WO2004054541)  

   To mix a ketofen solution of 12.5mg/mL for systemic injection:

   To mix a ketofen solution of 12.5mg/mL for systemic injection: