VTA Cell Counts
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Cell counts for total number of cells and TH-positive cells in the VTA of rats from the literature.
| Paper | Total Neurons | TH+ Cells | TH cells /mm2 | TH cells/ mm3 | -Technique |
|---|---|---|---|---|---|
| Gondré-Lewis 2016 | 61,000 ± 3700 | 252 ± 13 | Stereology for total neurons, IHC for TH cells | ||
| Gomide 2005 | 12,000 ± 1600 | 1,190 ± 130 | Stereology (typo in volume — paper says x10, not x1000) | ||
| Healy-Stoffel 2014 | 16,641±567 | 1,724±81 | Stereology | ||
| Mukherjee pilot | 71 | 15,625 | IHC, extrapolating from 40 um section |
References
Gondré-Lewis et al., Stereological Analyses of Reward System Nuclei in Maternally Deprived/Separated Alcohol Drinking Rats J Chem Neuroanat. 2016 October ; 76(Pt B): 122–132 PMID 26939765
Healy-Stoffel et al. Differential Effects of Intrastriatal 6- Hydroxydopamine on Cell Number and Morphology in Midbrain Dopaminergic Subregions of the Rat Brain Res. 2014 Jul 29;1574:113-9 PMID 24924804
Gomide et al. Dopamine cell morphology and glial cell hypertrophy and process branching in the nigrostriatal system after striatal 6-OHDA analyzed by specific sterological tools. Int J Neurosci. 2005 Apr;115(4):557-82. PMID 15804725