Changes

Jump to navigation Jump to search

BrdU (view source)

Revision as of 13:26, 10 March 2009

16,732 bytes added ,  13:26, 10 March 2009
added long list of refs to get
Line 47: Line 47:     
Incorporation of BrdU makes cells more sensitive to radiation damage.
 
Incorporation of BrdU makes cells more sensitive to radiation damage.
 +
 +
=Pharmacokinetics=
 +
 +
Papers to look up re: pharmacokinetics
 +
 +
1:
 +
The toxic effect of 5-bromodeoxyuridine on cultured epithelial cells.
 +
LITTLEFIELD JW, GOULD EA.
 +
J Biol Chem. 1960 Apr;235:1129-33. No abstract available.
 +
PMID 14417553 [PubMed - OLDMEDLINE]
 +
 +
Related Articles Free article at journal site
 +
 +
2:
 +
Relative stability to thermal denaturation of deoxyribonucleic acid (DNA) preparations containing bromodeoxyuridine.
 +
KIT S, HSU TC.
 +
Biochem Biophys Res Commun. 1961 Jun 2;5:120-4. No abstract available.
 +
PMID 13756434
 +
 +
3:
 +
Quantitative studies of incorporation of exogenous thymidine and 5-bromodeoxyuridine into deoxyribonucleic acid of mammalian cells in vitro.
 +
KRISS JP, REVESZ L.
 +
Cancer Res. 1961 Oct;21:1141-7. No abstract available.
 +
PMID 14459708
 +
 +
4:
 +
Incorporation of unnatural pyrimidine bases into deoxyribonucleic acid of mammalian cells.
 +
EIDINOFF ML, CHEONG L, RICH MA.
 +
Science. 1959 Jun 5;129(3362):1550-1.
 +
PMID 13658990
 +
 +
5:
 +
The fate of 5-bromodeoxyuridine, 5-bromodeoxycytidine, and 5-iododeoxycytidine in man.
 +
KRISS JP, MARUYAMA Y, TUNG LA, BOND SB, REVESZ L.
 +
Cancer Res. 1963 Feb;23:260-8. No abstract available.
 +
PMID 14035826  Free article at journal site
 +
 +
6:
 +
Effect of 5-bromodeoxyuridine incorporation on survival of cultured mammalian cells.
 +
HAKALA MT.
 +
Biochim Biophys Acta. 1962 Nov 26;61:815-23. No abstract available.
 +
PMID 13952011 [PubMed - OLDMEDLINE]
 +
 +
Related Articles
 +
 +
7:
 +
A chromosome study of radiation sensitization by 5-bromodeoxyuridine.
 +
SOMERS CE, HUMPHREY RM.
 +
Exp Cell Res. 1963 Mar;30:208-17. No abstract available.
 +
PMID 13978156
 +
 +
8:
 +
Radiosensitization of a mammalian cell line with 5-bromodeoxyuridine.
 +
DELIHAS N, RICH MA, EIDINOFF ML.
 +
Radiat Res. 1962 Oct;17:479-91. No abstract available.
 +
PMID 14026711 [PubMed - OLDMEDLINE]
 +
 +
Related Articles
 +
 +
9:
 +
The distribution and fate of bromodeoxyuridine and bromodeoxycytidine in the mouse and rat.
 +
KRISS JP, REVESZ L.
 +
Cancer Res. 1962 Feb;22:254-65. No abstract available.
 +
PMID 14459709  Free article at journal site
 +
 +
10:
 +
Increase in radiosensitivity to ionizing radiation related to replacement of thymidine in mammalian cells with 5-bromodeoxyuridine.
 +
Dewey WC, Humphrey RM.
 +
Radiat Res. 1965 Dec;26(4):538-53. No abstract available.
 +
PMID 5849707
 +
 +
11:
 +
Structures of 5-bromodeoxyuridine and 5-bromouridine.
 +
Iball J, Morgan CH, Wilson HR.
 +
Nature. 1966 Mar 19;209(5029):1230-2. No abstract available.
 +
PMID 5956313
 +
 +
12:
 +
Intra-arterial 5-bromodeoxyuridine and x-ray therapy.
 +
Bagshaw MA, Doggett RL, Smith KC, Kaplan HS, Nelsen TS.
 +
Am J Roentgenol Radium Ther Nucl Med. 1967 Apr;99(4):886-94. No abstract available.
 +
PMID 6021392
 +
 +
13:
 +
Theoretical evaluation of a limitation in the use of pyrimidine analogs in radiation therapy.
 +
Suit HD.
 +
Radiology. 1966 Dec;87(6):1065-8 passim. No abstract available.
 +
PMID 5926229
 +
 +
14:
 +
Comparative aspects of the pharmacology of the antimetabolites.
 +
Karnofsky DA, Young CW.
 +
Fed Proc. 1967 Jul-Aug;26(4):1139-45. No abstract available.
 +
PMID 4226285
 +
 +
15:
 +
Loss of labelled DNA from rat brain following injections of precursors with high specific radioactivity. II. DNA labelled with 5-[131I]iodo-2'-deoxyuridine and 5-[82Br]bromo-2'-deoxyuridine.
 +
Merits I, Cain JC.
 +
Biochim Biophys Acta. 1970;209(2):327-38. No abstract available.
 +
PMID 5453521
 +
 +
16:
 +
The turnover of isotopically labelled DNA in vivo in developing, adult and Scrapie-affected mouse brain.
 +
Kimberlin RH, Shirt DB, Collis SC.
 +
J Neurochem. 1974 Jul;23(1):241-8. No abstract available.
 +
PMID 4859554
 +
 +
17:
 +
Comparison of bromodeoxyuridine labeling indices obtained from tissue sections and flow cytometry of brain tumors.
 +
Nagashima T, Hoshino T, Cho KG, Senegor M, Waldman F, Nomura K.
 +
J Neurosurg. 1988 Mar;68(3):388-92.
 +
PMID 3278075
 +
 +
18:
 +
Improvement of the bioavailability of the anti-herpes virus agent BVDU by use of 5'-O-alkoxycarbonyl derivatives with increased metabolic stability.
 +
Boyd MR, Cole M, Harnden MR, Luk K, Rush MA, Sutton D, Hodge RA.
 +
J Antimicrob Chemother. 1986 Oct;18 Suppl B:207-13.
 +
PMID 3793660
 +
 +
19:
 +
Cell kinetic studies of in situ human brain tumors with bromodeoxyuridine.
 +
Hoshino T, Nagashima T, Murovic J, Levin EM, Levin VA, Rupp SM.
 +
Cytometry. 1985 Nov;6(6):627-32.
 +
PMID 2998714
 +
 +
20:
 +
Bioavailability of bromodeoxyuridine in dogs and toxicity in rats.
 +
Phuphanich S, Levin VA.
 +
Cancer Res. 1985 May;45(5):2387-9. No abstract available.
 +
PMID 3986781  Free article at journal site
 +
 +
21:
 +
Pharmacological evaluation of intravenous delivery of 5-bromodeoxyuridine to patients with brain tumors.
 +
Russo A, Gianni L, Kinsella TJ, Klecker RW Jr, Jenkins J, Rowland J, Glatstein E, Mitchell JB, Collins J, Myers C.
 +
Cancer Res. 1984 Apr;44(4):1702-5.
 +
PMID 6704976  Free article at journal site
 +
 +
22:
 +
Incorporation and persistence of 5-bromodeoxyuridine in newborn rat tissue DNA.
 +
Likhachev AJ, Tomatis L, Margison GP.
 +
Chem Biol Interact. 1983 Aug 15;46(1):31-8.
 +
PMID 6616707
 +
 +
23:
 +
Incorporation of 5-bromodeoxyuridine into DNA in newborn rat tissues.
 +
Margison GP, Likhachev AJ, Tomatis L.
 +
Chem Biol Interact. 1980 Jun;30(3):297-303.
 +
PMID 7379209
 +
 +
24:
 +
Tumor uptake of radiolabeled pyrimidine bases and pyrimidine nucleosides in animal models--III. 2'-[82Br]-bromo-2'-deoxyuridine.
 +
Lee YW, Knaus EE, Wiebe LI.
 +
Int J Nucl Med Biol. 1979;6(2):109-112. No abstract available.
 +
PMID 113355
 +
 +
25:
 +
Bromodeoxyuridine incorporation into DNA of human leukemia cells is not concentration dependent.
 +
Powell BL, Gregory BW, Kute TE, Morgan TM, Lyerly ES, Capizzi RL.
 +
Cytometry. 1990;11(3):438-41.
 +
PMID 2340778
 +
 +
26:
 +
Immunocytochemical detection of 5'-bromodeoxyuridine incorporation in the central nervous system of the mouse.
 +
del Rio JA, Soriano E.
 +
Brain Res Dev Brain Res. 1989 Oct 1;49(2):311-7.
 +
PMID 2805336
 +
 +
27:
 +
In situ analysis of cell kinetics in human brain tumors. A comparative immunocytochemical study of S phase cells by a new in vitro bromodeoxyuridine-labeling technique, and of proliferating pool cells by monoclonal antibody Ki-67.
 +
Morimura T, Kitz K, Budka H.
 +
Acta Neuropathol. 1989;77(3):276-82.
 +
PMID 2922990
 +
 +
28:
 +
Steady-state arterial and hepatic venous plasma concentrations of 5-bromo-2'-deoxyuridine and 5-iodo-2'-deoxyuridine in animals--drugs which are subject to both splanchnic and extra-splanchnic elimination.
 +
Wagner JG, Stetson PL, Knol JA, Andrews JC, Walker-Andrews S, Knutsen CA, Johnson N, Prieskorn D, Terrio P, Yang Z, et al.
 +
Sel Cancer Ther. 1989 Winter;5(4):193-203.
 +
PMID 2623384
 +
 +
29:
 +
Tissue-specific pharmacodynamics of 5-bromo-2'-deoxyuridine incorporation into DNA in VX2 tumor-bearing rabbits.
 +
Stetson PL, Maybaum J, Wagner JG, Averill DR, Wollner IS, Knol JA, Johnson NJ, Yang ZM, Preiskorn D, Smith P, et al.
 +
Cancer Res. 1988 Dec 1;48(23):6900-5.
 +
PMID 3180098  Free article at journal site
 +
 +
30:
 +
Persistence of 5-bromo-2'-deoxyuridine in tissues of rats after exposure in early life.
 +
Ward JM, Henneman JR, Osipova GYu, Anisimov VN.
 +
Toxicology. 1991;70(3):345-52.
 +
PMID 1771641
 +
 +
31:
 +
cis-trans-isomerization of [E]-5-(2-bromovinyl)-2,2'-anhydrouridine in vivo in rats.
 +
Szinai I, Veres Z, Szabolcs A, Gács-Baitz E, Ujszászy K, Dénes G.
 +
Xenobiotica. 1991 Mar;21(3):359-69.
 +
PMID 1650515
 +
 +
32:
 +
The dependence of halogenated pyrimidine incorporation and radiosensitization on the duration of drug exposure.
 +
Lawrence TS, Davis MA, Maybaum J, Stetson PL, Ensminger WD.
 +
Int J Radiat Oncol Biol Phys. 1990 Jun;18(6):1393-8.
 +
PMID 2370189
 +
 +
33:
 +
Cyclization-activated prodrugs. Basic esters of 5-bromo-2'-deoxyuridine.
 +
Saari WS, Schwering JE, Lyle PA, Smith SJ, Engelhardt EL.
 +
J Med Chem. 1990 Sep;33(9):2590-5.
 +
PMID 2391697
 +
 +
34:
 +
Effect of lithium on incorporation of bromodeoxyuridine and tritiated thymidine into human parathyroid cells.
 +
Saxe A, Gibson G.
 +
Arch Surg. 1993 Aug;128(8):865-9.
 +
PMID 8343059
 +
 +
35:
 +
Evaluation of a new lipophilic prodrug 3', 5'-dioctanoyl-5-bromodeoxyuridine (BrdU-C8) suspended in Lipiodol as a radiosensitizer for the treatment of AH136B tumor.
 +
Ohara C, Beppu T, Yamaguchi Y, Masuda Y, Fukushima S, Kawaguchi T, Ogawa M.
 +
Anticancer Res. 1993 May-Jun;13(3):655-60.
 +
PMID 8391245
 +
 +
36:
 +
Measurement of incorporation of bromodeoxyuridine into DNA by high performance liquid chromatography using a novel fluorescent labelling technique.
 +
Stratford MR, Dennis MF.
 +
Int J Radiat Oncol Biol Phys. 1992;22(3):485-7.
 +
PMID 1735684
 +
 +
37:
 +
Kinetics of bromodeoxyuridine elimination from human colon cancer cells in vitro and in vivo.
 +
Lawrence TS, Davis MA, Stetson PL, Maybaum J, Ensminger WD.
 +
Cancer Res. 1994 Jun 1;54(11):2964-8.
 +
PMID 8187082  Free article at journal site
 +
 +
38:
 +
Differential expressions of the topoisomerase II alpha and II beta mRNAs in developing rat brain.
 +
Watanabe M, Tsutsui K, Tsutsui K, Inoue Y.
 +
Neurosci Res. 1994 Feb;19(1):51-7.
 +
PMID 8008235
 +
 +
39:
 +
Preparation, characterization and release of microencapsulated bromodeoxyuridine.
 +
Maysinger D, Filipović-Grcić J, Alebić-Kolbah T.
 +
Life Sci. 1994;54(1):27-34.
 +
PMID 8255166
 +
 +
40:
 +
Regional differences in bromodeoxyuridine uptake, expression of Ki-67 protein, and nucleolar organizer region counts in glioblastoma multiforme.
 +
Onda K, Davis RL, Wilson CB, Hoshino T.
 +
Acta Neuropathol. 1994;87(6):586-93.
 +
PMID 8091951
 +
 +
41:
 +
The application of 5-bromodeoxyuridine in the management of CNS tumors.
 +
Freese A, O'Rourke D, Judy K, O'Connor MJ.
 +
J Neurooncol. 1994;20(1):81-95. Review.
 +
PMID 7807187
 +
 +
42:
 +
Comparison of bromodeoxyuridine uptake and MIB 1 immunoreactivity in medulloblastomas determined with single and double immunohistochemical staining methods.
 +
Onda K, Davis RL, Edwards MS.
 +
J Neurooncol. 1996 Aug;29(2):129-36.
 +
PMID 8858517
 +
 +
43:
 +
Incorporation of 5-iodo-2'-deoxyuridine and 5-bromo-2'-deoxyuridine into rodent DNA as determined by neutron activation analysis.
 +
Kitchin KT, Brown JL.
 +
Anal Biochem. 1995 Aug 10;229(2):180-7.
 +
PMID 7485970
 +
 +
44:
 +
Pharmacokinetics and bioavailability of 5-ethyl-2'-deoxyuridine and its novel (5R,6R)-5-bromo-6-ethoxy-5,6-dihydro prodrugs in mice.
 +
Cheraghali AM, Kumar R, Knaus EE, Wiebe LI.
 +
Drug Metab Dispos. 1995 Feb;23(2):223-6.
 +
PMID 7736915
 +
 +
45:
 +
Long-term oral application of 5-bromo-2-deoxyuridine does not reliably label proliferating immune cells in the LEW rat.
 +
Jecker P, Beuleke A, Dressendörfer I, Pabst R, Westermann J.
 +
J Histochem Cytochem. 1997 Mar;45(3):393-401.
 +
PMID 9071321  Free article at journal site
 +
 +
46:
 +
Fluorescein-labeled tyramide strongly enhances the detection of low bromodeoxyuridine incorporation levels.
 +
Van Heusden J, de Jong P, Ramaekers F, Bruwiere H, Borgers M, Smets G.
 +
J Histochem Cytochem. 1997 Feb;45(2):315-9.
 +
PMID 9016320  Free article at journal site
 +
 +
47:
 +
Regional pharmacokinetics of 5-bromo-2'-deoxyuridine and 5-fluorouracil in dogs: hepatic arterial versus portal venous infusions.
 +
Kuan HY, Smith DE, Ensmiger WD, Knol JA, DeRemer SJ, Yang Z, Stetson PL.
 +
Cancer Res. 1996 Oct 15;56(20):4724-7.
 +
PMID 8840990  Free article at journal site
 +
 +
48:
 +
Bromodeoxyuridine uptake by early liver metastases in rats: a comparison of the hepatic artery and portal vein infusion routes.
 +
Ishida H, Iwama T, Yoshinaga K, Gonda T, Idezuki Y.
 +
Surg Today. 1998;28(8):822-9.
 +
PMID 9719004
 +
 +
49:
 +
Assessment of correlation between skin target site free drug concentration and the in vivo topical antiviral efficacy in hairless mice for (E)-5-(2-bromovinyl)-2'-deoxyuridine and acyclovir formulations.
 +
Afouna MI, Mehta SC, Ghanem AH, Higuchi WI, Kern ER, De Clercq E, El-Shattawy HH.
 +
J Pharm Sci. 1998 Aug;87(8):917-21.
 +
PMID 9687333
 +
 +
50:
 +
Changes in cell-cycle kinetics during the development and evolution of primate neocortex.
 +
Kornack DR, Rakic P.
 +
Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1242-6.
 +
PMID 9448316  Free article in PMC | at journal site
 +
 +
51:
 +
Bromodeoxyuridine alternating with radiation for advanced uterine cervix cancer: a phase I and drug incorporation study.
 +
Eisbruch A, Robertson JM, Johnston CM, Tworek J, Reynolds KR, Roberts JA, Lawrence TS.
 +
J Clin Oncol. 1999 Jan;17(1):31-40.
 +
PMID 10458215
 +
 +
52:
 +
Determination of (E)-5-(2-bromovinyl)-2'-deoxyuridine in plasma and urine by capillary electrophoresis.
 +
Olgemöller J, Hempel G, Boos J, Blaschke G.
 +
J Chromatogr B Biomed Sci Appl. 1999 Apr 16;726(1-2):261-8.
 +
PMID 10348194
 +
 +
53:
 +
Elimination of nonspecific radioactivity from [76Br]bromide in PET study with [76Br]bromodeoxyuridine.
 +
Lu L, Bergström M, Fasth KJ, Wu F, Eriksson B, Långström B.
 +
Nucl Med Biol. 1999 Oct;26(7):795-802.
 +
PMID 10628559
 +
 +
54:
 +
[76Br]Bromodeoxyuridine, a potential tracer for the measurement of cell proliferation by positron emission tomography, in vitro and in vivo studies in mice.
 +
Ryser JE, Bläuenstein P, Rémy N, Weinreich R, Hasler PH, Novak-Hofer I, Schubiger PA.
 +
Nucl Med Biol. 1999 Aug;26(6):673-9.
 +
PMID 10587106
 +
 +
55:
 +
Analysis of 76Br-BrdU in DNA of brain tumors after a PET study does not support its use as a proliferation marker.
 +
Gudjonssona O, Bergström M, Kristjansson S, Wu F, Nyberg G, Fasth KJ, Långström B.
 +
Nucl Med Biol. 2001 Jan;28(1):59-65.
 +
PMID 11182565
 +
 +
56:
 +
[76Br]Bromodeoxyuridine PET in tumor-bearing animals.
 +
Gardelle O, Roelcke U, Vontobel P, Crompton NE, Guenther I, Bläuenstein P, Schubiger AP, Blattmann H, Ryser JE, Leenders KL, Kaser-Hotz B.
 +
Nucl Med Biol. 2001 Jan;28(1):51-7.
 +
PMID 11182564
 +
 +
57:
 +
Use of 5-[(76)Br]bromo-2'-fluoro-2'-deoxyuridine as a ligand for tumour proliferation: validation in an animal tumour model.
 +
Borbath I, Grégoire V, Bergström M, Laryea D, Långström B, Pauwels S.
 +
Eur J Nucl Med Mol Imaging. 2002 Jan;29(1):19-27. Epub 2001 Nov 22.
 +
PMID 11807603
 +
 +
58:
 +
A method for pulse and chase BrdU-labeling of early chick embryos.
 +
Hämmerle B, Tejedor FJ.
 +
J Neurosci Methods. 2002 Dec 31;122(1):59-64.
 +
PMID 12535764
 +
 +
59:
 +
Label-retaining cells in the rat pancreas: location and differentiation potential in vitro.
 +
Duvillié B, Attali M, Aiello V, Quemeneur E, Scharfmann R.
 +
Diabetes. 2003 Aug;52(8):2035-42.
 +
PMID 12882920  Free article at journal site
 +
 +
60:
 +
Brivudine: a herpes virostatic with rapid antiviral activity and once-daily dosing.
 +
Rabasseda X.
 +
Drugs Today (Barc). 2003 May;39(5):359-71. Review.
 +
PMID 12861349
 +
 +
61:
 +
Visualization of proliferating cells in the adult mammalian brain with the aid of ribonucleotide reductase.
 +
Zhu H, Wang ZY, Hansson HA.
 +
Brain Res. 2003 Jul 11;977(2):180-9.
 +
PMID 12834878
 +
 +
62:
 +
Tumor distribution of bromodeoxyuridine-labeled cells is strongly dose dependent.
 +
Kyle AH, Huxham LA, Baker JH, Burston HE, Minchinton AI.
 +
Cancer Res. 2003 Sep 15;63(18):5707-11.
 +
PMID 14522888  Free article at journal site
 +
 +
63:
 +
Direct assessment of drug penetration into tissue using a novel application of three-dimensional cell culture.
 +
Kyle AH, Huxham LA, Chiam AS, Sim DH, Minchinton AI.
 +
Cancer Res. 2004 Sep 1;64(17):6304-9.
 +
PMID 15342419  Free article at journal site
 +
 +
64:
 +
Thymidine analogs are transferred from prelabeled donor to host cells in the central nervous system after transplantation: a word of caution.
 +
Burns TC, Ortiz-González XR, Gutiérrez-Pérez M, Keene CD, Sharda R, Demorest ZL, Jiang Y, Nelson-Holte M, Soriano M, Nakagawa Y, Luquin MR, Garcia-Verdugo JM, Prósper F, Low WC, Verfaillie CM.
 +
Stem Cells. 2006 Apr;24(4):1121-7. Epub 2005 Dec 22.
 +
PMID 16373692  Free article at journal site
 +
 +
65:
 +
Gadofluorine m uptake in stem cells as a new magnetic resonance imaging tracking method: an in vitro and in vivo study.
 +
Giesel FL, Stroick M, Griebe M, Tröster H, von der Lieth CW, Requardt M, Rius M, Essig M, Kauczor HU, Hennerici MG, Fatar M.
 +
Invest Radiol. 2006 Dec;41(12):868-73.
 +
PMID 17099425
 +
 +
66:
 +
Ki-67 correlates with in vivo bromodeoxyuridine labeling index in operable breast cancer.
 +
Goodson WH, Moore DH, Waldman FM.
 +
J Clin Oncol. 2006 Aug 10;24(23):3809; author reply 3809. No abstract available.
 +
PMID 16896010
 +
 +
67:
 +
An ELISA-based method for the quantification of incorporated BrdU as a measure of cell proliferation in vivo.
 +
Behl B, Klos M, Serr M, Ebert U, Janson B, Drescher K, Gross G, Schoemaker H.
 +
J Neurosci Methods. 2006 Nov 15;158(1):37-49. Epub 2006 Jun 15.
 +
PMID 16780957
 +
 +
68:
 +
Dienogest inhibits BrdU uptake with G0/G1 arrest in cultured endometriotic stromal cells.
 +
Fu L, Osuga Y, Morimoto C, Hirata T, Hirota Y, Yano T, Taketani Y.
 +
Fertil Steril. 2008 May;89(5 Suppl):1344-7. Epub 2007 May 23.
 +
PMID 17511992
 +
 +
69:
 +
Bromodeoxyuridine labeling index as an indicator of early tumor response to preoperative radiotherapy in patients with rectal cancer.
 +
Gasinska A, Skolyszewski J, Popiela T, Richter P, Darasz Z, Nowak K, Niemiec J, Biesaga B, Adamczyk A, Bucki K, Malecki K, Reinfuss M, Kowalska T.
 +
J Gastrointest Surg. 2007 Apr;11(4):520-8.
 +
PMID 17436139  Free article in PMC | at journal site
 +
 +
70:
 +
The origin of deoxynucleosides in brain: implications for the study of neurogenesis and stem cell therapy.
 +
Spector R, Johanson CE.
 +
Pharm Res. 2007 May;24(5):859-67. Epub 2007 Mar 20. Review.
 +
PMID 17372683
    
[[Category:Flavor Preference]]
 
[[Category:Flavor Preference]]
Retrieved from "https://wiki.houptlab.org/wiki/Special:MobileDiff/1991"

Navigation menu