Changes

Jump to navigation Jump to search
m
→‎Selenate Dosage: corrected links/calculations for selenate (was selenite before)
Line 4: Line 4:  
== Selenate Dosage ==
 
== Selenate Dosage ==
   −
To test selenate attenuation of CFNP, rats will be injected with 1 ml/kg of 0.5 mg/ml Na2SeO3 in 0.15 M NaCl, (so 0.5 mg/kg selenate), 2 hours before conditioning.
+
To test selenate attenuation of CFNP, rats will be injected with 1 ml/kg of 0.5 mg/ml Na2SeO4 in 0.15 M NaCl, (so 0.5 mg/kg selenate), 2 hours before conditioning.
   −
* Sodium Selenate Na2SeO3 from 2021-2-16 from [https://www.sigmaaldrich.com/catalog/product/sial/71950?lang=en&region=US&gclid=EAIaIQobChMI0Lqo_9S38AIVWW5vBB0u2g1xEAAYASAAEgJ-9fD_BwE Millipore-Sigma S8295-25G]  
+
* Sodium Selenate Na2SeO4 from 2021-2-16 from [https://www.sigmaaldrich.com/catalog/product/sigma/s8295?lang=en&region=US&cm_sp=Insite-_-caSrpResults_srpRecs_srpModel_sodium%20selenate-_-srpRecs3-1]  
   −
* MW 172.94, CAS Number 10102-18-8 , [https://pubchem.ncbi.nlm.nih.gov/substance/329763654 PubChem Substance ID 329763654]
+
* MW 188.95, CAS Number 13410-01-0, [https://pubchem.ncbi.nlm.nih.gov/compound/25960]
 
  −
* 0.5 mg/ml Na2Se03 is 2.89 mM, or 8.67 mOsm (assuming complete dissociation into 2 Na+ and 1 SeO3- ions)
  −
 
  −
* So OK to mix 0.5 mg Na2Se03 in 1 ml of 0.15 M NaCl, resulting in a 309 mOsm solution that is still near isotonic (300mOsM).
      +
* 0.5 mg/ml Na2Se04 is 2.65 mM, or 7.95 mOsm (assuming complete dissociation into 2 Na+ and 1 SeO4- ions)
    +
* So OK to mix 0.5 mg Na2SeO4 in 1 ml of 0.15 M NaCl, resulting in a 308 mOsm solution that is still near isotonic (300mOsM).
    
==Data==
 
==Data==
45

edits

Navigation menu