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JCD Clozapine-N-Oxide Taste Aversion (view source)
Revision as of 14:44, 27 June 2023
, 14:44, 27 June 2023→Agenda
Arrived 2023-2-6.
Arrived 2023-2-6.
'''Day 0: Water removed''' (2023-3-4)
'''Day 0: Water removed''' (2023-6-19)
'''Days 1 - 11: Water Restriction''' (2023-3-5 - 2023-3-15)
'''Days 1 - 11: Water Restriction''' (2023-6-20 - 2023-6-30)
Weigh mice daily. Ad lib food. Water access on consecutive days at noon: 3h, 3h, 3h, 1h, 1h, 1h, 30min, 30 min, 10 min, 10 min, 10 min.
Weigh mice daily. Ad lib food. Water access on consecutive days at noon: 3h, 3h, 3h, 1h, 1h, 1h, 30min, 30 min, 10 min, 10 min, 10 min.
Mice given water bottle and empty bottle, alternating position.
Mice given water bottle and empty bottle, alternating position.
In the afternoon (~5pm) , mice will be given a supplemental access to water for 30 min.
In the afternoon (~4pm), mice will be given supplemental access to water for 30 min.
'''Day 12: Conditioning Day''' (2023-3-16)
'''Day 12: Conditioning Day''' (2023-3-16)
Mice are given 10-min access to 0.125% saccharin solution, then injected with vehicle (10 ml/kg) or 1, 3 or 10 mg/kg
Mice are given 10-min access to 0.125% saccharin solution, then injected with vehicle (10 ml/kg) or 1, 3 or 30 mg/kg