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Rats typically display lying-on-belly (LOB) behavior in response to LiCl-induced malaise. The time to onset of LOB behavior has been shown to decrease as the dose of LiCl increases (2), so the time to onset of LOB can be used to infer the magnitude of LiCl-induced malaise. This experiment aims to determine if sodium selenate pretreatment weakens the toxic effects of LiCl by measuring the time to onset of LOB after LiCl (0.15M, 20 ml/kg, i.p.) administration in selenate-pretreated vs control rats.
Rats typically display lying-on-belly (LOB) behavior in response to LiCl-induced malaise. The time to onset of LOB behavior has been shown to decrease as the dose of LiCl increases (2), so the time to onset of LOB can be used to infer the magnitude of LiCl-induced malaise. This experiment aims to determine if sodium selenate pretreatment weakens the toxic effects of LiCl by measuring the time to onset of LOB after LiCl (0.15M, 20 ml/kg, i.p.) administration in selenate-pretreated vs control rats.
+{| class="wikitable"
+|+ Drug Injection Summary
+|-
+! Subject !! Day1 (6ml/kg) !! Day2 (12ml/kg) !! Day3 (20ml/kg) !! Day4 (12ml/kg) !! Day5 (12ml/kg) !! Day6 (12ml/kg)
+|-
+| MBF01 || NaCl/NaCl || Sel/NaCl || Sel/LiCl || NaCl/LiCl || Sel/LiCl || NaCl/NaCl
+|-
+| MBF02 || Sel/NaCl || Sel/LiCl || NaCl/LiCl || NaCl/NaCl || NaCl/LiCl || Sel/NaCl
+|-
+| MBF03 || Sel/LiCl || NaCl/LiCl || Sel/NaCl || NaCl/NaCl || Sel/LiCl || Sel/NaCl
+|-
+| MBF04 || NaCl/LiCl || NaCl/NaCl || NaCl/NaCl || Sel/LiCl || NaCl/LiCl || Sel/NaCl
+|-
+| MBF05 || NaCl/LiCl || Sel/LiCl || NaCl/NaCl || Sel/NaCl || NaCl/NaCl || NaCl/LiCl
+|-
+| MBF06 || Sel/LiCl || Sel/NaCl || Sel/NaCl || NaCl/LiCl || NaCl/NaCl || Sel/LiCl
+|}
=Agenda=
=Agenda=