Changes

Abdo (1994) reported on the effects of administering sodium selenate in the drinking water for 13 weeks. It was estimated that the "no-observed adverse level" in rat was 0.4 mg/kg per day of sodium selenate for 13 weeks. Doses of 0.6 mg/kg or 1.1 mg/kg  per day for 13 weeks caused changes in mortality, body weight depression, decreased water consumption, and renal papillary lesions. However, these were chronic studies so that rats received a total dose of 54.6 mg/kg or 100.1 mg/kg sodium selenate over 13 weeks.

Abdo (1994) reported on the effects of administering sodium selenate in the drinking water for 13 weeks. It was estimated that the "no-observed adverse level" in rat was 0.4 mg/kg per day of sodium selenate for 13 weeks. Doses of 0.6 mg/kg or 1.1 mg/kg  per day for 13 weeks caused changes in mortality, body weight depression, decreased water consumption, and renal papillary lesions. However, these were chronic studies so that rats received a total dose of 54.6 mg/kg or 100.1 mg/kg sodium selenate over 13 weeks.

Aasif Mandvi ran a [https://www.cc.com/video/jucn2a/the-daily-show-with-jon-stewart-a-simple-plot story] on selenium pollution of Idaho rivers as a consequence of phosphate mining.

Aasif Mandvi ran a [https://web.archive.org/web/20240423122448/https://www.cc.com/video/jucn2a/the-daily-show-with-jon-stewart-a-simple-plot story] on selenium pollution of Idaho rivers as a consequence of phosphate mining.

==Selenium Ingestion and Aversions==

==Selenium Ingestion and Aversions==

Corcoran NM et al. 2010b.  Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancer. Br J Cancer. 103:462-8. PMID 20648008

Corcoran NM et al. 2010b.  Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancer. Br J Cancer. 103:462-8. PMID 20648008

Mandvi, A. A Simple Plot. The Daily Show with Jon Stewart, aired June 14, 2012. https://www.cc.com/video/jucn2a/the-daily-show-with-jon-stewart-a-simple-plot

Mandvi, A. A Simple Plot. The Daily Show with Jon Stewart, aired June 14, 2012. https://web.archive.org/web/20240423122448/https://www.cc.com/video/jucn2a/the-daily-show-with-jon-stewart-a-simple-plot

Reid ME et al.  2004 A report of high-dose selenium supplementation: response and toxicities. J Trace Elem Med Biol 18:69–74 PMID 15487766

Reid ME et al.  2004 A report of high-dose selenium supplementation: response and toxicities. J Trace Elem Med Biol 18:69–74 PMID 15487766

van Eersel J et al. 2010. Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models. PNAS 107:13888-93. PMID 20643941

van Eersel J et al. 2010. Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models. PNAS 107:13888-93. PMID 20643941