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DMJ Valproate and Saccharin CTA (view source)
Revision as of 14:04, 3 April 2021
, 14:04, 3 April 2021added valproate source
Test if pre-conditioning injection of sodium valproate enhances conditioned taste aversion induced by low dose of LiCl in females vs. male rats
Test if pre-conditioning injection of sodium valproate enhances conditioned taste aversion induced by low dose of LiCl in females vs. male rats, as a comparison of another HDAC inhibitor to sodium butyrate used in our earlier studies.
Sodium Valproate [https://www.sigmaaldrich.com/catalog/product/sigma/p4543?lang=en®ion=US Millipore Sigma P4543-25G] MW 166.19
Some evidence that valproate can induce CTA when administered after tastant intake, so in this experiment valproate administered 15 min before the start of saccharin consumption in the hopes that any backward conditioning will be weak. Valproate also has a longer half-life than butyrate, so may be in the system longer.
==Data==
==Data==