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DMF Sodium Butyrate and Saccharin-LiCl CTA (view source)
Revision as of 11:06, 24 November 2020
, 11:06, 24 November 2020updated extinction dates, fixed some typos
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Test if systemic Sodium Butyrate (NaB), an HDAC inhibitor, enhances CTA learning .
Test if systemic Sodium Butyrate (NaB), an HDAC inhibitor, enhances CTA learning .
+
+(see replication to increase N at [[DMG Sodium Butyrate and Saccharin-LiCl CTA]])
+<br>
A more strict replication of [https://houptlab.org/papers/pdfs/Houpt065.pdf Kwon and Houpt, Brain Research, 1333 (2010) 36–47], PMID: 20346924 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871962/ PMCID: PMC2871962].
A more strict replication of [https://houptlab.org/papers/pdfs/Houpt065.pdf Kwon and Houpt, Brain Research, 1333 (2010) 36–47], PMID: 20346924 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871962/ PMCID: PMC2871962].
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ad lib water returned after final injection overnight.
ad lib water returned after final injection overnight.
−* Rats 1-8 : male, Rats 10-18: female
+* Rats 1-8 : male, Rats 9-16: female
* All rats: saccharin
* All rats: saccharin
* All rats: LiCl (0.15M, 3ml/kg)
* All rats: LiCl (0.15M, 3ml/kg)
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−'''Days 13 - ??: Preference Tests''' (October 22 - ?? October , 2020)
+'''Days 13 - 22: Preference Tests''' (October 22 - November 1, 2020)
−Rats CTA acquisition and extinction was measured with 48-h, 2-bottle preference tests. Rats were given 24-h free access to both 75 mM NaCl and water bottles, alternating position for 6 days.
+Rats CTA acquisition and extinction was measured with 48-h, 2-bottle preference tests. Rats were given 24-h free access to both 0.125% saccharin and water bottles, alternating position for 10 days.
[[Category:Flavor Preference]]
[[Category:Flavor Preference]]
[[Category:Taste Aversion]]
[[Category:Taste Aversion]]