1,137
edits
Changes
Jump to navigation
Jump to search
Line 1:
Line 1: + + + Line 55:
Line 58: − + Line 61:
Line 64: − + − +
DMF Sodium Butyrate and Saccharin-LiCl CTA (view source)
Revision as of 10:06, 24 November 2020
, 10:06, 24 November 2020updated extinction dates, fixed some typos
Test if systemic Sodium Butyrate (NaB), an HDAC inhibitor, enhances CTA learning .
Test if systemic Sodium Butyrate (NaB), an HDAC inhibitor, enhances CTA learning .
(see replication to increase N at [[DMG Sodium Butyrate and Saccharin-LiCl CTA]])
<br>
A more strict replication of [https://houptlab.org/papers/pdfs/Houpt065.pdf Kwon and Houpt, Brain Research, 1333 (2010) 36–47], PMID: 20346924 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871962/ PMCID: PMC2871962].
A more strict replication of [https://houptlab.org/papers/pdfs/Houpt065.pdf Kwon and Houpt, Brain Research, 1333 (2010) 36–47], PMID: 20346924 [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871962/ PMCID: PMC2871962].
ad lib water returned after final injection overnight.
ad lib water returned after final injection overnight.
* Rats 1-8 : male, Rats 10-18: female
* Rats 1-8 : male, Rats 9-16: female
* All rats: saccharin
* All rats: saccharin
* All rats: LiCl (0.15M, 3ml/kg)
* All rats: LiCl (0.15M, 3ml/kg)
'''Days 13 - ??: Preference Tests''' (October 22 - ?? October , 2020)
'''Days 13 - 22: Preference Tests''' (October 22 - November 1, 2020)
Rats CTA acquisition and extinction was measured with 48-h, 2-bottle preference tests. Rats were given 24-h free access to both 75 mM NaCl and water bottles, alternating position for 6 days.
Rats CTA acquisition and extinction was measured with 48-h, 2-bottle preference tests. Rats were given 24-h free access to both 0.125% saccharin and water bottles, alternating position for 10 days.
[[Category:Flavor Preference]]
[[Category:Flavor Preference]]
[[Category:Taste Aversion]]
[[Category:Taste Aversion]]