1,158
edits
Changes
updated some dates, LiOr prep
| investigators = Nabi, Houpt
| investigators = Nabi, Houpt
| species = rat
| species = rat
| date = 2025-1-14
| date = 2026-1-14
| type = CTA
| type = CTA
| drugs = lithium orotate, lithium chloride
| drugs = lithium orotate, lithium chloride
===Agenda===
===Agenda===
Rats arrive (2026-1-20), n= 16 adult male Sprague Dawley rats (Charles River CD), individually housed in BRF 169.
Rats arrive (2026-1-20), n= 16 adult male Sprague Dawley rats d.o.b. 2025-????? (Charles River CD), individually housed in BRF 169.
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* 0.15 M LiCl, 6 ml/kg ip. (SNA02,05,08,11,14)
* 0.15 M LiCl, 6 ml/kg ip. (SNA02,05,08,11,14)
* 0.15 M LiOr, 6 ml/kg ip. (SNA03,06,09,12,15,16) (LiOr was more of a milky suspension)
* 0.15 M LiOr, 6 ml/kg ip. (SNA03,06,09,12,15,16) (LiOr was more of a milky suspension)
LiOr prepared as orotic acid added to 0.15M LiOH to make nominal 0.15M Li Orotate -- but did not go competely into solution, so injected "slurry"
ad lib water returned after final injection overnight.
ad lib water returned after final injection overnight.
'''Days 13 - 22: Preference Tests''' (2026-2-3 through 2026-2-13)
'''Days 13 - 34: Preference Tests''' (2026-2-3 through 2026-2-24)
Rats CTA acquisition and extinction was measured with 24-h, 2-bottle preference tests. Rats were given 24-h free access to both 0.125% saccharin and water bottles, alternating position for 10 days.
Rats CTA acquisition and extinction was measured with 24-h, 2-bottle preference tests. Rats were given 24-h free access to both 0.125% saccharin and water bottles, alternating position for 21 days.
[[Category:Taste Aversion]]
[[Category:Taste Aversion]]
[[Category:CTA Experiments]]
[[Category:CTA Experiments]]